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The Complete CCS Mnemonics Cheat Sheet for Step 3

HMMM

Harsh Moolani, MD, MPH

Mnemonics only help on CCS if they convert directly into orders. A memory trick that helps you recall a differential but doesn't tell you what to click next isn't pulling its weight in a timed case. This is a working reference of the mnemonics that actually hold up under exam pressure, organized by the situation you'll use them in.

Keep this open next to your practice cases and check whether each one earns its place in your own review — the goal is a short list you've actually internalized, not a long list you skim once.

First 60 Seconds / Triage Mnemonics

  • ABCs first, always: before any mnemonic below, airway, breathing, circulation still governs your very first orders in an unstable-appearing patient.
  • VS + Monitor + IV + O2: the default opening order bundle for almost any acute presentation — vital signs, cardiac monitor, IV access, and supplemental oxygen if indicated. Order it before you start narrowing the differential.

Chest Pain / Cardiac Don't-Miss

  • The "big five" chest pain killers: ACS, aortic dissection, pulmonary embolism, tension pneumothorax, esophageal rupture. Run through this list mentally before you commit to a benign diagnosis on any chest pain case.
  • MONA is outdated — order-by-indication instead: the old "morphine, oxygen, nitrates, aspirin" mnemonic gets marked wrong on CCS because oxygen and morphine aren't automatic anymore. Aspirin is near-universal; the rest depend on the actual presentation.

Abdominal Pain Localization

  • Quadrant-first thinking: RUQ (biliary, hepatic), epigastric (pancreatic, gastric, cardiac), RLQ (appendiceal, gynecologic), LLQ (diverticular, gynecologic). Let location narrow your initial order set before you order a shotgun panel.
  • Pancreatitis criteria as a checklist, not a mnemonic: rather than memorizing a scoring acronym, know the actual lab and clinical thresholds cold — CCS cares whether you order the right labs, not whether you can recite a mnemonic name.

Altered Mental Status

  • AEIOU-TIPS: alcohol, epilepsy/electrolytes, insulin (hypo/hyperglycemia), oxygen (hypoxia), uremia, trauma/temperature, infection, psychiatric, stroke/shock/space-occupying lesion. Use it as an order-generation checklist — for every letter, ask "what order rules this out?"

Electrolyte and Acid-Base Quick Checks

  • MUDPILES for anion gap acidosis: methanol, uremia, DKA, propylene glycol/paraldehyde, isoniazid/iron, lactic acidosis, ethylene glycol, salicylates. Useful for generating your differential once you see a wide anion gap on the metabolic panel.
  • Peaked T waves, wide QRS → treat hyperkalemia before the potassium level even results if the EKG already shows it. Don't wait on a confirmatory lab when the rhythm strip is telling you what's happening.

Respiratory and Sepsis Triggers

  • Sepsis red flags as an order-trigger, not a trivia list: fever or hypothermia, tachycardia, tachypnea, altered mental status, and hypotension should each independently push you toward cultures, lactate, and early fluids rather than waiting to hit a formal score threshold.
  • COPD/asthma exacerbation severity cues: inability to speak in full sentences, accessory muscle use, and a silent chest are your cues to escalate respiratory support immediately rather than waiting on a blood gas result to confirm what you can already see.

Where Mnemonics Stop Helping

A mnemonic is a retrieval aid, not a substitute for knowing the actual order set. On CCS specifically, you're graded on what you click, not on whether you can recite a list out loud — so the real test is whether each item above still translates into a concrete order when you're under a ticking clock. If it doesn't, drop it and replace it with a mnemonic that maps directly to your order sheet.

Related Guides

Test whether these actually stick under time pressure — run a timed CCS case and see how many of these you reach for without looking back at this page.

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